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Organic
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Plant Based
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No Artificial Additives
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Third-Party Tested
Licorice
Licorice
With over 4,000 years of traditional use, Licorice root remains one of the most revered herbs for gastrointestinal mucosal comfort, immune support, respiratory wellness, healthy adrenal and stress response, and liver health.*
This certified organic Glycyrrhiza glabra root tincture is extracted at a 1:5 ratio in organic ethanol and purified water to preserve its full spectrum of glycyrrhizin, flavonoids, triterpenoids, isoflavonoids, and demulcent polysaccharides.* Vegan.*
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Organic
-
Plant Based
-
No Artificial Additives
-
Third-Party Tested
Supplement facts
Suggested use
Take 1 dropperful (0.7 mL) 2 to 3 times per day or as directed by your healthcare professional.
Shake before use.
Cautions and considerations
Do not use when pregnant or nursing unless recommended by your healthcare professional.
Keep out of reach of children.
Store in a cool, dry and dark place.
Pairs well with
Your product questions answered
Q: What is glycyrrhizin and how does it contribute to licorice root's wellness benefits?
A: Glycyrrhizin is the principal triterpene glycoside in Glycyrrhiza glabra root. When metabolized, it yields glycyrrhizic and glycyrrhetinic acid, which modulate the enzyme 11β-HSD2 — responsible for converting cortisol to cortisone. By influencing this pathway, glycyrrhizin supports the availability of endogenous cortisol activity and a healthy HPA axis tone without directly stimulating adrenal hormone production.* This unique mechanism contributes to licorice's role in supporting balanced stress response.*
Q: How does licorice root support GI mucosal health?
A: Licorice root's flavonoids stimulate mucin secretion and modulate prostaglandin synthesis and epithelial cytokines, while its polysaccharides provide demulcent coating throughout the GI and respiratory mucosa. This combination supports the integrity and comfort of sensitive digestive tissues, making licorice a valued botanical in protocols addressing GI mucosal wellness and healthy digestive function.*
Q: Are there any cautions with long-term use of licorice root?
A: Yes — glycyrrhizin-containing licorice preparations, when used in high doses or for extended periods, may affect fluid balance and electrolyte levels due to their influence on the 11β-HSD2 pathway. Individuals with hypertension, kidney concerns, or those on certain medications should consult their healthcare practitioner before use. Licorice is not recommended during pregnancy. Always use under the guidance of a qualified practitioner.*

Challenge
Traditional botanical remedies offer one of our greatest opportunities to reconnect with nature’s restorative intelligence. Adaptogenic botanicals like licorice provide gentle, targeted support for the body’s natural systems of resilience, helping nurture balance and vitality in the face of modern stressors.*
Biopure Health™ Licorice:
- Supports GI mucosal integrity, soothing sensitive digestive tissue and healthy digestive function*
- Promotes healthy immune function and balanced immune response through immunomodulatory activity*
- Supports upper respiratory mucosal health and soothing of sensitive throat tissue*
- Promotes balanced adrenal function and healthy HPA axis tone*
- Supports liver health and hepatic antioxidant function*
Solution
Licorice root (Glycyrrhiza glabra) has been valued across cultures for its adaptogenic and multi-system supportive properties.* Today, research continues to explore its roles in supporting the body’s natural balance and overall resilience.*
- Certified organic
- Extracted in low-allergenic organic sugarcane ethanol
- 1:5 full-spectrum strength ratio
Biopure Clean
As a full-spectrum extract, Licorice preserves the root’s complete bioactive intelligence, enabling a broader range of phytochemical synergy.*
Our extraction method retains the plant’s biological integrity and facilitates an optimal range of water-soluble (polar) and fat-soluble (non-polar) compounds, increasing the broad-spectrum action of the herb extract.*
Every raw ingredient is thoughtfully sourced and third-party tested for microbial and heavy-metal contaminants, in alignment with the high standards upheld across all Biopure Health products.*
Ingredients
- Organic Licorice (Glycyrrhiza glabra) root extract
- 1:5 herb strength ratio
- Other Ingredients: Filtered water and organic sugarcane ethanol (42-52%).
- Form: Liquid
- Free from the Top 9 Allergens
Holistic Outcomes
Flavonoids stimulate mucin secretion and modulate prostaglandin synthesis and epithelial cytokines; polysaccharides provide additional demulcent coating throughout GI and respiratory mucosa.*
Glycyrrhizin hydrolyzes to glycyrrhizic and glycyrrhetinic acid, which modulate 11β-HSD2 — the enzyme converting cortisol to cortisone — supporting available cortisol activity and healthy HPA axis tone without stimulating adrenal hormone production.*
Hepatic activities include Phase I/II enzyme modulation, beta-glucuronidase suppression, lipid peroxidation inhibition, and antifibrotic effects via TGF-beta and T helper cell balance regulation.*