• Biopure Health Liposomal Delivery System
  • Biopure Health Practitioner Formulated
  • Biopure Health Third-Party Tested
  • Biopure Health Vegan

Liposomal Melatonin

Liposomal Melatonin

5.0
Rated 5.0 out of 5 stars
3 Reviews

By passing the digestive bottleneck of conventional oral melatonin for fast, efficient sublingual absorption, liposomal melatonin supports healthy sleep onset, sleep quality, circadian rhythm balance, overnight antioxidant defense, and the body's natural glymphatic brain-clearing processes.*

 

This formula provides 4 mg of melatonin per dose in a nanoemulsified phosphatidylcholine liposomal base, with liposomes just 20–100 nm in size.* Vegan.*
$36.00
$36.00
No available purchase options for this selection.
Deliver Every

Free shipping on consumer orders over $99
  • Biopure Health Liposomal Delivery System
  • Biopure Health Practitioner Formulated
  • Biopure Health Third-Party Tested
  • Biopure Health Vegan
Supplement facts
Biopure Health
Suggested use

Take 1 pump by mouth, (Approx. 0.2mL), hold for 30 seconds before swallowing, or as directed by your healthcare professional.

Cautions and considerations

Do not use when pregnant or nursing unless recommended by your healthcare practitioner.

Keep out of reach of children.

Store in a cool, dry and dark place.

Pairs well with

Baikalin, PC Ecklonia Cava

Your product questions answered

Q: Why choose liposomal melatonin over standard melatonin tablets?

A: Conventional oral melatonin tablets are subject to first-pass hepatic metabolism, which can significantly reduce the amount of melatonin that reaches circulation. Biopure Liposomal Melatonin uses a nanoemulsified phosphatidylcholine liposomal delivery system (20–100 nm liposomes) designed for sublingual absorption directly through the oral mucosa — supporting earlier and more consistent peak plasma levels compared to standard oral formats.*

Q: What is the glymphatic system and how does melatonin support it?

A: The glymphatic system is the brain's waste-clearance network, which is primarily active during sleep. Healthy melatonin levels support deep, restorative sleep cycles — the same cycles that allow the glymphatic system to perform its natural overnight brain-clearing processes. Supporting healthy melatonin levels and sleep quality may therefore complement the body's natural nightly neurological maintenance routines.*

Q: Should Biopure Liposomal Melatonin be paired with a binder?

A: Biopure practitioners recommend pairing Liposomal Melatonin with a Biopure Binder™ such as Chlorella Pyrenoidosa or ZeoBind® as part of a comprehensive nighttime protocol. This combination supports the body's natural overnight detoxification and elimination processes. Consult your healthcare practitioner for personalized protocol guidance.*

View full details

Challenge

In today’s world, environmental and lifestyle-related stressors can place added demands on the body’s interconnected systems, potentially disrupting balance and impacting overall vitality.* This can create a need to foster restorative equilibrium and support healthy detoxification processes to help strengthen resilience and promote lasting vitality.*

Biopure Health™ Liposomal Melatonin:

  • Supports normal circadian rhythms and sleep-wake cycle regulation*
  • 2. Promotes healthy sleep onset, duration, and restorative sleep quality*
  • Supports healthy antioxidant and oxidative stress response*
  • Supports glymphatic function and the body's natural overnight brain-clearing processes*
  • Promotes healthy immune function and nightly cellular repair and recovery*
Biopure Health

Solution

Melatonin supports healthy circadian rhythms and deep, restorative sleep—key for nightly cellular repair and regeneration.* It also supports the body’s natural detoxification systems, including glymphatic function involved in brain and cellular health.*

In addition, melatonin supports immune health and contributes to the body’s redox balance by scavenging free radicals and supporting the activity of antioxidant enzymes.*

    BioPure Health’s Liposomal Melatonin delivers melatonin in nanonized liposomal phosphatidylcholine—a primary component of cell membranes—to promote optimal absorption and bioavailability.*

  • This advanced sublingual delivery bypasses the digestive system, allowing melatonin to enter the bloodstream quickly and support efficient cellular uptake.*
  • Our nanoemulsified liposomes are 1/10th the industry-standard size (20-100 nm vs. 200-1000 nm), enabling faster, more complete absorption when placed under the tongue.*
Biopure Health

Formula Intelligence

We carefully select highly purified phosphatidylcholine liposomes for our advanced sublingual delivery system. Our smaller liposomes (20-100 nm) support quick and efficient uptake through the tissues of the mouth, helping melatonin bypass the digestive system and directly enter the bloodstream.*

Ingredients
  • Melatonin 4mg
  • Other Ingredients: Water, glycerin, ethanol, tocofersolan, medium-chain triglycerides, highly purified phospholipids and natural mixed tocopherols.
  • Form: Liquid
  • Free from the Top 9 Allergens
Biopure Health

Holistic Outcomes

Exogenous melatonin is associated with reduced sleep onset latency and increased total sleep time.* Nanoemulsified liposomes (20–100 nm) are designed to support sublingual absorption directly through oral mucosa, bypassing first-pass hepatic metabolism for earlier and higher peak plasma concentrations vs. standard oral tablets.*

Melatonin crosses the blood-brain barrier freely and scavenges free radicals directly; its metabolites upregulate endogenous antioxidant enzymes (SOD, catalase, glutathione peroxidase).* Glymphatic system activity is tightly linked to sleep quality and circadian integrity — healthy melatonin levels may promote optimal nightly brain clearing and metabolic byproduct removal.*

Customer Reviews

5.0
Rated 5.0 out of 5 stars
Based on 3 reviews
Write a Review (Opens in a new window)
3 reviews
  • SR
    Sharon R.
    Verified Buyer
    19 hours ago
    Rated 5 out of 5 stars
    Much improved sleep

    I have been using Biopure Liposomal Melatonin right before bed each night for over a year now.

    It has reliably helped me fall asleep & stay asleep.

    Was this helpful?
  • TD
    Toni D.
    Verified Buyer
    6 days ago
    Rated 5 out of 5 stars
    The best

    My sleep has improved tenfold!

    Was this helpful?
  • LH
    Lynn H.
    2 months ago
    Rated 5 out of 5 stars
    A Bedtime Favorite

    I love the convenient liquid format and pleasant taste of Liposomal Melatonin. It's easy to use and a great product to keep on hand when I want extra support before bedtime. As always, Biopure Health delivers excellent quality.

    Was this helpful?